Encore Medspa

What is Hyperdilute Radiesse®?: 6 Questions Answered Now

womans neck and lower face with hands wearing plastic gloves on neck, getting ready for hyperdilute radiesse® treatment

In the world of aesthetic treatments, innovation continually brings forth solutions that combine science and artistry to enhance natural beauty. One such revolutionary treatment is Hyperdilute Radiesse® (HDR). Often hailed as “liquid gold,” HDR offers a unique approach to rejuvenating and remodeling the skin, providing both immediate and long-lasting results. Let’s delve into what makes HDR a standout in the realm of injectables.

What is Hyperdilute Radiesse® (HDR)?

Hyperdilute Radiesse® is an advanced injectable biostimulator derived from Radiesse®, an FDA-approved dermal filler. This filler, known for its efficacy in facial contouring and wrinkle reduction, is reconstituted with a customized blend to create HDR. The resulting solution is then injected into large areas such as the neck, lower face, arms, thighs, and buttocks. The primary objective? To stimulate the production of collagen and elastin, key components for youthful and resilient skin.

womans neck and lower face with hands wearing plastic gloves on neck, getting ready for hyperdilute radiesse® treatment

What Makes Hyperdilute Radiesse® Different?

Unlike traditional fillers, HDR offers a dual benefit. Initially, patients can observe immediate improvement in the treated areas. However, the true magic unfolds over the next few months as the body gradually absorbs the product. During this time, HDR stimulates the natural production of collagen and elastin, leading to firmer, smoother, and more youthful skin. The results are long-lasting, with the newly generated collagen providing enduring support without the need for dissolution, as required with hyaluronic acid (HA) fillers. Additionally, the non-surgical nature of HDR ensures minimal downtime, making it a convenient option for those with busy lifestyles.

What is the Downtime for HDR?

Post-treatment, patients might experience some bruising and mild swelling, typically lasting between 3 to 7 days. This minimal downtime allows most individuals to resume their daily activities shortly after the procedure.

How Does HDR Work?

Radiesse®, the base product for HDR, contains calcium hydroxyapatite (CaHA) microspheres suspended in a gel. This composition is scientifically proven to stimulate the production of organized collagen type III and elastin in the dermis. To create Hyperdilute Radiesse®, Radiesse® is mixed with lidocaine, saline, and potentially growth factors, resulting in a diluted formula that is easier to spread across larger skin areas. When injected, HDR works by integrating into the top layer of the dermis, where it initiates the formation of new collagen and elastin networks. This process effectively thickens the skin, smooths out wrinkles, and addresses crepey skin, all while maintaining a natural appearance that avoids the puffiness often associated with traditional HA fillers.

Where Can HDR be Injected?

HDR’s versatility allows it to be used in various body areas. It can be injected into the neck, lower face, arms, and thighs to enhance skin thickness and smooth wrinkles. Additionally, HDR can address skin laxity and augment volume-deficient areas such as the cheeks and buttocks. For significant volume enhancement, especially in the buttocks, multiple syringes (ranging from 6 to 20) may be required per treatment session.

Nurse injecting hyperdilute radiesse treatment to middle-aged woman's neck, encore medspa, walnut creek

Who is a Good Candidate for Hyperdilute Radiesse® (HDR)?

Hyperdilute Radiesse® is suitable for a wide range of individuals. Ideal candidates include those with crepey, loose skin, and unwanted wrinkles or lines resulting from aging. It is also an excellent choice for individuals seeking a fuller, rounder, or lifted buttocks. Before undergoing HDR, a consultation with a qualified nurse is essential to ensure there are no medical contraindications and to tailor the treatment to the patient’s specific needs.


Hyperdilute Radiesse® (HDR) stands out as a groundbreaking treatment that combines the benefits of immediate aesthetic enhancement with the long-term rejuvenation of the skin. Its ability to stimulate natural collagen and elastin production makes it a powerful tool in the fight against aging, providing results that are both natural and enduring. For those seeking to revitalize their appearance without the need for surgery or extensive downtime, HDR truly is the “liquid gold” solution.

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